The effect of Apple seeds Pyrus malus L. on some fertility parameters of white rats

Abstract

The present study aimed to determine the effects that can be performed by eating apples seeds Pyrus malus L. in some standards of white rat males fertility during effects on hormones level LH, FSH and Testosterone and spermatogenesis.
The effect of apples seeds in fertility standards has been performed, 36 adult rat males have been used and distributed into two groups G1, G2 according to the administered dose in addition to the control group C, it included all the animals age groups (7-8) weeks and ages (12-14) months , the first and the second group have been given apple seeds with 2% and 4%, respectively of the weight of the wet provender ,while the control group has been given the normal provender for 50 days. Animals were sacrified after 24 hr. of last dose , by using the heart puncture blood was obtained for hormonal study , testes were obtained for histological study and compare with control group the result show:
1- significance increase (p<0.05) in the concentration of LH and Testosterone in both groups in comparison with the control group, and an increase in the concentration of the follicle stimulating hormone FSH reaching the significance degree in the two groups for age (12-14) months only.
2- histological measurements that made on the testis showed a significance increase (P <0.05) in the diameters of seminiferous tubules, thickness of its lining.
3- a significant increase (P<0.05) in the number of spermatogonia when compared with the control group.