Estimating Mediation and direct effects of the multiple model with application Kidney

Abstract

This paper presented a study of the analysis of the mediation of a multi-model and the knowledge of the role of these variables in the transfer of the effect of the independent variable to the dependent variable. In this article, the delta method was used to estimate the standard error and because this method violates a number of assumptions, especially with small sampling sizes, the method of shoeboxes was used to overcome such problems. According to the results obtained from the application for this model, it was found that the shoe bass method is better than the Delta method according to numerical results.